Two sample MR report
DBI_Dendritic Cell (DC) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.2445055 | 0.7912567 | 0.7865339 |
| Weighted median | 4 | 0.2361137 | 0.0520639 | 0.0000058 |
| Inverse variance weighted | 4 | 0.2373512 | 0.0412281 | 0.0000000 |
| Simple mode | 4 | 0.2335972 | 0.0626330 | 0.0335836 |
| Weighted mode | 4 | 0.2345654 | 0.0658695 | 0.0377916 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1065463 | 2 | 0.9481210 |
| Inverse variance weighted | 0.1066283 | 3 | 0.9910303 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0035414 | 0.3911438 | 0.993598 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.03e-05 | 0 | TRUE | 0.4348043 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
